ZFDM rats will be discontinued on March 31, 2027.

Left Hos:ZFDM-Lepr^fa, fa/+ Right Hos:ZFDM-Lepr^fa, fa/fa

▶ Origin

ZF colony at Tokyo Medical University (Tokyo, Japan)

▶ Genetic control

Outbred

▶ Obesity*

Early onset (6-12wk)

*Characteristics of fa/fa male rats in the ZFDM strains.

▶ Diabetes*

Young to middle age-onset (10-20wk)

*Characteristics of fa/fa male rats in the ZFDM strains.

▶ Special diet

Not needed

▶ Breeding

♀(fa/+) × ♂(fa/fa)

▶ Attention

fa/fa male and fa/+ male are available for sale.
Breeding is prohibited.

▶ References

Yokoi, N. et al. A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat. J. Diabetes Res. 2013, 103731 (2013).