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Mice HR−１
  HRM-2
  NSY-Ay
Rats ZFDM
  OLETF & LETO
ZFDM (rat model of type 2 diabetes)

Rat model of type 2 diabetes
Efficient Breeding and Low Price
HR1

Left Hos:ZFDM-Leprfa, fa/+
Right Hos:ZFDM-Leprfa, fa/fa
  Characteristics of the ZFDM and ZDF strains. [1]
  ZFDM ZDF
Origin ZF colony at Tokyo Medical University
(Tokyo, Japan)		 ZF colony at Eli Lilly Research Laboratories (Indianapolis, IN)
Genetic control Outbred Inbred
Obesity* Early onset (6-12wk) Early onset (6-10wk)
Diabetes* Young to middle age-onset (10-20wk) Young age-onset (8-12wk)
Special diet Not needed Purina 5008
Breeding

 

♀(fa/+) × ♂(fa/fa)

♀(fa/+) × ♂(fa/+)

*Characteristics of fa/fa male rats in the ZFDM and ZDF strains.

[1] Yokoi, N. et al. A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat. J. Diabetes Res. 2013, 103731 (2013).		  
  Attention Breeding is prohibited.  

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