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Mice HR−1
  HRM-2
  HR/DeF1
  NSY
Rats ZFDM
  OLETF
  LETO
  SHR
  SHRSP
  WKY
etc. HR-AD diet
ZFDM rats (Hos:ZFDM-Leprfa, fa/fa and fa/+)

Rat model of type 2 diabetes
Efficient Breeding and Low Price
HR1

  Characteristics of the ZFDM and ZDF strains. [1]
  ZFDM ZDF
Origin ZF colony at Tokyo Medical University
(Tokyo, Japan)
ZF colony at Eli Lilly Research Laboratories (Indianapolis, IN)
Genetic control Outbred Inbred
Obesity* Early onset (6-12wk) Early onset (6-10wk)
Diabetes* Young to middle age-onset (10-20wk) Young age-onset (8-12wk)
Special diet Not needed Purina 5008
Breeding

 

♀(fa/+) × ♂(fa/fa)

♀(fa/+) × ♂(fa/+)


*Characteristics of fa/fa male rats in the ZFDM and ZDF strains.

[1] Yokoi, N. et al. A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat. J. Diabetes Res. 2013, 103731 (2013).
 
  Attention Breeding is prohibited.  

References         Order