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Mice HR−1
  HRM-2
  HR/DeF1
  NSY
Rats ZFDM
  OLETF
  LETO
  SHR
  SHRSP
  WKY
etc. HR-AD diet
Hos:HR/DeF1 Melanin-possessing hairless mice

(HR-1 × HR/DE) F1 hairless mice

HR1

  Proper name Hos:(HR-1×HR/De)F1  
  Description  Homozygous mutants (Hrhr/Hrhr) show normal development of the first hair coat (first hair cycle). Starting at 2 weeks of age, they lose their hair coat rapidly and completely due to an abnormal second hair cycle [1, 2]. At weaning (~3 weeks of age), they are completely hairless [3].  
  Appearance pigmented, without hair, unaffected  
  Genotype hrhr/hrhr  
  Reseach ultraviolet radiation induced melanogenesis  
  Development  We stareted to cross HR/De male mice to HR-1/Hos female mice in 2009. We named them Hos:HR/DeF1.  
  Attention Breeding is prohibited.  
  References

[1] Brooke, H.C. 1926. Hairless mice. J. Hered. 17, 173–174.

[2] Sundberg, J. P. & King, L. E. Morphology of hair in normal and mutant laboratory mice. Eur. J. Dermatol. 11, 357–61

[3] Suzuki, O., Koura, M., Noguchi, Y., Uchio-Yamada, K. & Matsuda, J. Zygosity determination in hairless mice by PCR based on Hr(hr) gene analysis. Exp. Anim. 62, 267–73 (2013).

 

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